256935 Probability sampling pregnant women in an urban core: A case study from the National Children's Study

Monday, October 29, 2012

Louise H. Flick, DrPH, MPE , Epidemiology Department, Saint Louis University, School of Public Health, St Louis, MO
Vetta Sanders Thompson, PhD , George Warren Brown School/ Institute of Public Health, Washington University in St. Louis, St. Louis, MO
Kate E. Beatty, MPH , School of Public Health, Saint Louis University, St Louis, MO
Grant W. Farmer, MPH , School of Public Health, St. Louis University, St. Louis, MO
Amanda S. Harrod, MPH , School of Public Health, Saint Louis University, St. Louis, MO
Nicole I. Weinstein, MSW , St. Louis City Field Office, National Children's Study, Battelle Centers for Public Health Research, St Louis, MO
Lisa John, PhD , Battelle Centers for Public Health Research and Evaluation, St Louis, MO
Allison King, MD, MPH , Program in Occupational Therapy and the Department of Pediatrics, Washington University in St. Louis, St Louis, MO
Laura W. Bernaix, PhD, RN , School of Nursing, Southern Illinois University Edwardsville, Edwardsville, IL
Elaina Murray, BS , School of Public Health, Saint Louis University, St Louis, MO
Margaret Callon, MSW , Epidemiology Department, Saint Louis University, St Louis, MO
BACKGROUND: Obtaining a probability sample of pregnant women presents challenges, particularly in an urban core. We summarize the challenges encountered during a pilot study of the National Children's Study (NCS), the methods used, and how representative the sample was of city births. The NCS will follow 100,000 prenatally recruited children until age 21 to examine the effects of environment on health. Current data stem from a recruitment pilot addressing one inner city Primary Sampling Unit (PSU) from a multistage national probability sample. Eligible women reside in randomly selected segments of the PSU and are pregnant or trying to conceive. Challenges include multiple native languages, poverty, low literacy levels, and mistrust of research.

METHODS: After listing all households (HH) in 15 segments within the PSU, we recruited door-to-door in 2011. Recruitment was enhanced through community engagement and media messaging. Analyses used descriptive statistics to compare characteristics (age, education, etc.) of eligible women and women consented to 2009 birth certificates. RESULTS: We listed 13,850 dwellings, contacted approximately 95% of HHs and enumerated 28.5%. By January 2012, we identified 200 eligible women and consented 150 (64.7%). The recruited women were 45% African-American and 21% did not graduate from high school. Recruited women were older, more educated, less likely to be African-American and more likely to be Hispanic than city births. We discuss possible explanations for these variances including segment formation and differential consent rates by race/ethnicity.

CONCLUSIONS: Results emphasize the challenges of probability sampling urban pregnant women in an inner city.

Learning Areas:
Public health or related research

Learning Objectives:
1. Identify issues related to probability sampling pregnant women 2. Discuss challenges of door-to-door recruitment in the inner city

Keywords: Pregnancy, Research

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I have been the principal or co-investigator on multiple federally and foundation funded grants and contracts focusing on maternal child health.My scientific interests have included the effects of mental illness on pregnancy and birth outcomes, tobacco use in pregnancy and adloescent pregnancy and childrearing.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.