256986 Mortality for Peripheral Artery Disease and Coronary Artery Disease in the Korean population: 5-15 Years Follow-Up

Sunday, October 28, 2012

Shin Yi Jang , Cardiovascular Imaging Center, Samsung Medical Center, Seoul, South Korea
Eun Young Ju, MPH , Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul, South Korea
Sung-Il Cho , Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul, South Korea
Seung Wook Lee , Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul, South Korea
Seung Woo Park , Division of Cardiology, Department of Medicine, Samsung Medical Center, Seoul, South Korea
Duk-Kyung Kim, PhD, MD , Division of Cardiology, Cariovascular Imaging Center, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Purpose The objective of this study is to analyze long-term survival of the subjects with peripheral artery disease (PAD), and coronary artery disease (CAD). Methods The sample included 4,526 Korean patients aged ≥45 years who were hospitalized from 1994 through 2004. 405 subjects had PAD confirmed by computed tomography angiography, while 3,475 subjects had CAD confirmed by cardiac catheterization in Cardiac & Vascular Center among PAD or CAD patients, Samsung Medical Center. Mortality data were obtained from all participants between 1994 and 2009 from the Statistics Korea. All-cause mortality was measured at 5 to15 years. Results The mean age (years) of PAD subjects was 65.1 (8.4) and that of CAD subjects was 62.4 (8.7) (p<0.001). For age group, 45 to 64 year-old group was 45.2% in PAD and 59.6 % in CAD. During the 5 to 15 years follow-up, all-cause cumulative mortality rate were 31.8% in PAD and 28.2% in CAD. The mean survival time was 8.77 (0.24) years in PAD and 11.4 (0.88) years in CAD. Ten years survival rate was 59% in PAD and 71% in CAD. The independent predictors of mortality were included, but not limited to, age, diabetes, and chronic kidney disease (CKD) in PAD and age, male gender, diabetes, dyslipidemia, smoking, CKD and anemia in CAD. Interestingly, overweight and obesity showed lower hazard ratio in PAD or CAD group. Conclusion In this study, we found that cardiovascular risk factors contributed to mortality. However, it seems that there is no similarity between PAD and CAD for their mortality rate.

Learning Areas:
Biostatistics, economics
Chronic disease management and prevention
Epidemiology
Public health or related research

Learning Objectives:
The objective of this study is to analyze long-term survival of the subjects with peripheral artery disease and coronary artery disease.

Keywords: Chronic (CVD), Mortality

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I designed, analyzed and wrote this study.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.