257094 Latent classes of injection risk behavior in a cohort of young injection drug users

Tuesday, October 30, 2012 : 8:30 AM - 8:45 AM

Mary Ellen Mackesy-Amiti, PhD , Division of Epidemiology and Biostatistics, University of Illinois at Chicago, School of Public Health, Chicago, IL
Lorna Finnegan, PhD , College of Nursing, University of Illinois at Chicago, Chicago, IL
Lawrence J. Ouellet, PhD , Division of Epidemiology and Biostatistics, University of Illinois at Chicago, School of Public Health, Chicago, IL
Elizabeth T. Golub, PhD, MPH , Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Holly Hagan, PhD , Institute for AIDS Research, National Development and Research Institutes, Inc., New York, NY
Sharon M. Hudson, PhD , Research and Evaluation Department, Kaiser Permanente Southern California, Pasadena, CA
Mary H. Latka, PhD , Aurum Insitute for Health Research, Johannesburg, Gauteng, South Africa
Richard Garfein, PhD , Division of Global Public Health, University of California San Diego, La Jolla, CA
Latent class analysis was used to identify classes of injection risk behavior in a sample of young injection drug users (IDUs) enrolled in the Collaborative Injection Drug Users Study III, and eligible for participation in the Drug Users Intervention Trial (DUIT). The risk behaviors included were frequency of sharing the following: 1) syringes, 2) cookers, 3) cottons, and 4) rinse water; 5) number of syringe-sharing partners; 6) frequency of using a new sterile syringe when dividing drugs in a syringe; and 7) frequency of cleaning needles with bleach when using a shared syringe. Four risk classes were identified: 1) overall low risk (33%), 2) equipment sharing only (22%), 3) moderate risk characterized by low-frequency sharing of syringes (19%), and 4) overall high risk (27%). Subjects were assigned to their most likely class, and multinomial logistic regressions were performed for each covariate. Women and younger IDUs were more likely to belong to the high-risk class; Black and Hispanic IDUs were more likely than White IDUs to belong to the low-risk class. The high-risk class had higher rates of homelessness, income from illicit activities, alcohol use, and non-injection drug use. The low-risk class was distinguished by fewer injection partners, and the low-risk and equipment-only classes had lower frequencies of injection compared to the moderate and high-risk classes. The risk classes had similar levels of HIV/HCV transmission knowledge, but differed significantly on peer norms for syringe sharing and self-efficacy for safer injection. Participation in the intervention trial did not vary by class membership.

Learning Areas:
Public health or related research
Social and behavioral sciences

Learning Objectives:
Describe four latent classes of injection risk behavior.

Keywords: Injection Drug Users, HIV Risk Behavior

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am the principal investigator of a federally funded grant focusing on the use of mixture modeling in the analysis of HIV risk behavior among injection drug users.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

Back to: 4043.0: HIV and Injection Drug Use