261565 Vivitrol Use in Los Angeles County: An Evaluation of Medication-Assisted Treatment

Tuesday, October 30, 2012

Sarah J. Cousins, MPH , Intergrated Substance Abuse Programs, University of California, Los Angeles, Los Angeles, CA
Loretta L. Denering, MS , Integrated Substance Abuse Programs, University of California, Los Angeles, Los Angeles, CA
Desiree Crevecoeur-MacPhail, Ph.D. , Integrated Substance Abuse Programs, University of California, Los Angeles, Los Angeles
Richard Rawson, PhD , Integrated Substance Abuse Programs, University of California, Los Angeles, Los Angeles, CA
Introduction: Vivitrol, when used in conjunction with psychosocial treatment, can significantly decrease the urge to use opiates and alcohol; thereby reducing the chances of relapse. Vivitrol is the long-acting (30-day) injectable form of Naltrexone which blocks the mu-opioid receptors in the brain. These receptors are responsible for the “high” or “buzz” experienced when alcohol is consumed. If receptors are blocked, the “high” is no longer experienced and cravings for alcohol are reduced. Prior implementations of medication assisted treatment (MAT) also indicated that counselor attitudes play a major role in medication use by treatment participants. Methods: In 2010, Los Angeles County began a pilot test Vivitrol within three treatment programs. To address counselor attitudes toward MAT, educational sessions were also provided to counselors to increase their knowledge about Vivitrol and buy-in. Counselors were surveyed before and 3 months post-educational groups. With regard to substance abuse treatment participants, after a physical exam to determine eligibility, they were given Vivitrol. Data were collected on participants' urge to drink and medication side effects weekly for the first four weeks (with baseline at the time of the initial shot) and monthly thereafter for as long as the participant was in treatment. Results: Counselor attitudes, although mixed in the beginning of the pilot, improved after training and education. Participants reported significant drops in their cravings and reduced primary drug use. Conclusion: Vivitrol is a feasible MAT within community based settings for individuals with chronic alcohol/opiate use problems.

Learning Areas:
Chronic disease management and prevention
Clinical medicine applied in public health
Program planning
Public health or related organizational policy, standards, or other guidelines
Social and behavioral sciences

Learning Objectives:
*To know that Vivitrol is an evidence based medically-assisted-treatment to reduce cravings among alcohol users. *To know that Vivitrol is an evidence based medically-assisted-treatment to reduce cravings among opiate users. *To know that Vivitrol is a feasible treatment tool within community-based treatment centers *To identify at least 2 benefits of Vivitrol

Keywords: Alcohol, Treatment

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am an M.P.H. candidate at UCLA, where I have also served as a research analyst for approximately 5 years. I have served as key project staff on various federal grants, and statewide and county evaluation projects including the Los Angeles County Evaluation System (LACES) evaluation of Vivitrol. I have co-authored published several works on addiction treatment.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.