264592 Determinants of carotid-femoral pulse wave velocity in healthy Korean

Sunday, October 28, 2012

Shin Yi Jang , Cardiovascular Imaing Center, Samsung Medical Center, Seoul, South Korea
Eun Young Ju, MPH , Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul, South Korea
Eun Hee Huh , Cardiovascular Center, Samsung Medical Center, Seoul, South Korea
Jung Hyun Kim , Cardiovascular Center, Samsung Medical Center, Seoul, South Korea
Seung Woo Park, PhD, MD , Division of Cardiology, Department of Medicine, Cariovascular Imaging Center, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Duk-Kyung Kim , Division of Cardiology, Department of Medicine, Cariovascular Imaging Center, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Purpose The aim of this study is to show normal value of carotid-femoral pulse wave velocity (cfPWV) according to age group, gender, prehypertension, dyslipidemia, smoking and obesity in healthy Korean, and to investigate association between cfPWV and prehypertension, dyslipidemia, smoking, and obesity. Methods We had an arterial stiffness clinical trial on 116 normal subjects who were 20 to 69 year-old in no evidence of cardiovascular disease, cerebrovascular accident, hypertension, diabetes mellitus or lung cancer at the Cardiac and Vascular Center from February 2010 to May 2011. Results Distribution of cfPWV by age group showed increasing mean value as aged. For cfPWV by age group and gender, male subjects showed higher cfPWV than female (P<0.001). For cfPWV by age group and blood pressure classification, cfPWV of prehypertensive group was higher than that of normotensive group (P<0.001). cfPWV by age group and dyslipidemia, current smoking, or obesity was shown in Figure 4, 5 and 6 (P<0.001). In multiple linear regression, prehypertension was highly associated with cfPWV after adjustment for age, gender and confounding factors (P<0.001). Conclusions The cfPWV has been shown to be associated with aging, gender, prehypertension, dyslipidemia, current smoking, and obesity in healthy Korean. And, we showed associated between cfPWV and prehypertension. and prehypertension.

Learning Areas:
Chronic disease management and prevention
Epidemiology

Learning Objectives:
To show normal value of carotid-femoral pulse wave velocity according to age group, gender, prehypertension, dyslipidemia, smoking and obesity in healthy Korean, and to investigate association between cfPWV and prehypertension, dyslipidemia, smoking, and obesity.

Keywords: Chronic (CVD), Aging

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I designed, analyzed, and wrote the study.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.