273870 Meta-analysis of the association between body mass index and health-related quality of life among children and adolescents, assessed using the PedsQL index

Monday, October 29, 2012

Zia UL Haq, MBBS, MPH , Public Health, University of Glasgow, Glasgow, United Kingdom
To explore the relationships between BMI and overall, physical and psychosocial health-related quality of life (HRQoL) in children and adolescents. A systematic review was conducted, in accordance with PRISMA guidelines. Medline, Embase, PsycINFO and the Web of Knowledge were searched for relevant articles. Inclusion was restricted to participants under 20 years of age, assessed using the PedsQL index. Random effects meta-analysis, meta-regression and cumulative meta-analysis were conducted. Heterogeneity was assessed using the I2 statistic, and potential publication and small study bias using funnel plots and Egger's test. Eleven eligible studies provided 35 estimates of effect size, derived from 13,210 study participants. Based on self report, children and adolescents with higher than normal BMI had significantly reduced total, physical and psychosocial HRQoL with a clear dose relationship across all categories. Among obese children/adolescents, the overall score was reduced by 10.6 points (95% CI 14.0, 7.2, p<0.001). Parents reported the same pattern but a larger effect size. The total parental score for obese children/adolescents was reduced by 18.9 points (95% CI 26.6, 11.1, p<0.001). No significant publication or small study bias was observed. Parents over-estimate the impact of obesity on the HRQoL of their children. Nonetheless, obese children/adolescents have significantly reduced overall, physical and psychosocial HRQoL.

Learning Areas:
Advocacy for health and health education
Chronic disease management and prevention
Public health or related education
Public health or related research
Social and behavioral sciences

Learning Objectives:
Demonstrate to clinicians, public health physicians and others to educate children and their parents about the potential adverse effect of obesity on their HRQoL

Keywords: Obesity, Quality of Life

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am the principal investigator on study "Meta-analysis of the association between body mass index and health-related quality of life among children and adolescents, assessed using the PedsQL index". My scientific interest is related obesity and relationship with health-related quality of life & health implications.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.