3423.0 Environmental exposures and biological variability: Defining the exposome in public health research

Monday, October 29, 2012: 4:30 PM - 6:00 PM
Oral
This session will explore the exposome -- the interplay between environmental exposures, biological variability, and public health. Understanding how exposures from our environment, diet, lifestyle, etc. interact with our own unique characteristics such as genetics, physiology, and epigenetics to impact our health is an important area of study for environmental public health. This session will look at several areas related to the exposome, including: 1) How epigenetic mechanisms can be used to explain how environmental exposure during pregnancy can affect children’s health; 2) Associations between exposure to PM 2.5 and cardiovascular disease using biomarkers of effect; 3)How traditional cardiovascular disease risk factors predict acrolein metabolite levels in a population based study; and 4)The use of PON1 as a biomarker of susceptibility to pesticide exposure in Mexican-american children and the implications of this for public health.
Session Objectives: 1. Describe how epigenetic mechanisms can be used to explain how environmental exposure during pregnancy can affect children’s health 2. Explain the association between exposures to PM 2.5 and biomarkers of cardiovascular effects 3. Describe how the PON1 enzyme can be used as a biomarker of susceptibility to organophosphate pesticide exposure.
Organizer:
Moderator:

4:30pm
Environmental exposures during pregnancy in Mexican-American women and their effects on epigenetics in newborns
Nina Holland, PhD, Paul Yousefi, MPH, Karen Huen, MPH, PhD, Raul Aguilar, PhD, Vitaly Volberg, MPH, Lisa Barcellos, PhD, Hong Quach, Asa Bradman, PhD and Brenda Eskenazi, PhD
4:50pm
PM2.5 and cardiovascular disease associations using biomarkers of effect: An environmental public health tracking study
Kathleen M. Navarro, MPH, Jennifer K. Mann, MPH, PhD, Thomas E. McKone, PhD and John R. Balmes, MD
5:10pm
Traditional cardiovascular disease risk factors predict acrolein metabolite level in a population-based study
Natasha DeJarnett, MPH, Daniel Conklin, PhD, John A. Myers, PhD, Ihab Hamzeh, MD, Stephen Wagner, MD, Atul Chugh, MD, Matthew Zahn, MD, David J. Tollerud, MD, MPH, Deirdre Higdon, MSN, ANP-BC, Carrie Becher, MPH, Bradley Wyatt, MPH, Tiffany Ciszewski, BSS, Daniel Riggs, MS, Sumanth Prabhu, MD and Aruni Bhatnagar, PhD
5:30pm
PON1 as a biomarker of susceptibility to pesticide exposure in Mexican-American children: Implications for public health
Karen Huen, MPH, PhD, Kim Harley, PhD, Asa Bradman, PhD, Brenda Eskenazi, PhD and Nina Holland, PhD

See individual abstracts for presenting author's disclosure statement and author's information.

Organized by: Environment

CE Credits: Medical (CME), Health Education (CHES), Nursing (CNE), Public Health (CPH) , Masters Certified Health Education Specialist (MCHES)

See more of: Environment