Urinary phthalate metabolite concentrations among custodians using green cleaners
Methods: Sixty-eight custodians provided four urine samples per shift (first void, before shift, end of shift and before bedtime). During each hour of the work shift, trained observers recorded cleaning tasks, and the type of product used (traditional or EPP). Five different phthalates metabolites MEHP, MMP, MBzP, MEP, MnBP corresponding to DEHP, DBP, BBP DEP, DBP were quantified in the urine using Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS).
Results: Geometric mean (standard deviation) urinary levels MEHP, MPB and MBzP are 6.9 (3.3), 20 (3.2), 8.8 (2.6) ug/g, respectively. For MBZP, we observed significantly (p=0.001) higher levels among custodians using traditional cleaners >4hrs. Custodians with >4hrs traditional cleaners use had higher end of shift MBzP urinary levels (19.5 ug/g) as compared to custodians using EPPS (13.1 ug/g). We will report urinary metabolite levels among custodians using EPPs and traditional cleaners during different times of the shift.
Conclusion: Our results suggest that different species of urinary phthalate metabolites measured in urine may be associated with occupational exposure.
Learning Areas:Occupational health and safety
Compare the urinary phthalate metabolite concentrations among custodians as they transitioned from traditional cleaners to the use of “green” or Environmentally Preferable Products (EPP). Identify species of urinary phthalate metabolites that may be associated with occupational exposures.
Keyword(s): Occupational Health, Occupational Exposure
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Any relevant financial relationships? No
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