Medication adherence among breast cancer survivors: Predictive validity of the protection motivation theory
Objective: To examine the predictive validity of Protection Motivation Theory (PMT) to assess adherence to aromatase inhibitors among breast cancer survivors.
Methods: A valid, reliable questionnaire was mailed to 288 breast cancer patients enrolled at a University-based medical center. The Morisky Medication Adherence Scale (MMAS) was used to measure survivors' medication adherence. 145 patients returned completed surveys (response rate to a 54%).
Results: 38% of the survivors were non-adherent to their medications including six who had discontinued therapy against doctors' orders. The level of protection motivation was positively and significantly correlated with adherence (r=0.310). Multiple regression revealed that coping appraisal was a better predictor of adherence (β=0.437) than threat appraisal, which was not correlated with adherence. Pearson's Correlation revealed that the PMT constructs of self-efficacy (r=0.485) and response efficacy (r=0.206) were positively correlated with adherence while response cost (r=-0.235) showed a negative correlation. Among the individual constructs of the PMT, self-efficacy was the only significant predictor of adherence (β = 0.429).
Conclusion: The coping appraisal portion of the PMT was useful in explaining breast cancer survivors' medication adherence. Those who work with survivors should consider using this PMT construct in their patient education and materials.
Learning Areas:Chronic disease management and prevention
Other professions or practice related to public health
Public health or related education
Public health or related research
Social and behavioral sciences
Systems thinking models (conceptual and theoretical models), applications related to public health
Describe the constructs of the Protection Motivation Theory (PMT) in relation to breast cancer recurrence. Describe how the constructs of the PMT explain breast cancer survivors’ motivation and adherence to Aromatase Inhibitors. Explain how to use the constructs of the PMT in communication with and programs to improve medication adherence breast cancer survivors.
Keyword(s): Adherence, Breast Cancer
Qualified on the content I am responsible for because: I am a doctoral student in the Health Education program at the University of Toledo. This project entitled "Medication adherence among breast cancer survivors: Predictive validity of the protection motivation theory" is a part of my thesis project for my masters degree in Pharmacy Administration.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.