Insufficient sleep, depression, and self-rated health in adult cancer survivors
Cross-sectional data from the 2010 Behavioral Risk Factor Surveillance System (BRFSS) involving adults cancer survivors were used for this study (n = 1,427). Perceived insufficient sleep (past 30 days), the primary exposure of interest, and was categorized into two groups (< 14 days vs. ≥ 14 days). The Patient Health Questionnaire 8 (PHQ-8) item scale was used to estimate the prevalence of current depression, mediator of interest, and was categorized into two groups (Present vs. Absent). HRQOL constructs measuring poor “self-rated health”, “physical health”, & “social functioning” (past 30 days) were the outcomes of interest and each was categorized into two groups (< 14 days vs. ≥ 14 days). Logistic regression models were used to examine if insufficient sleep was directly associated with HRQOL and if current depression mediates the relationship, adjusting for all potential confounders. Statistical analysis accounted for complex sampling design of the BRFSS.
Current depression significantly mediated the effect of insufficient sleep on HRQOL. The proportion of effect mediated by current depression on Physical Health was 61%, followed by Social Functioning(58.4%), and General Health(41%), after adjusting for potential confounders.
Adult cancer survivors with insufficient sleep are at risk for depressive symptoms which in turn has implications for Health-Related Quality of Life outcomes.
Public health or related research
Identify the role of insufficient sleep, current depression, on Health-Related Quality of Life in adult cancer survivors.
Keywords: Cancer, Health Indices
Qualified on the content I am responsible for because: Subir Goyal is a doctoral student in epidemiology and his interests lie in the public health areas: cancer research, mental health, health related outcomes, etc.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.