Interest in genetic test feedback for risk of obesity: Findings from the pgen study
Tuesday, November 5, 2013
Genetic testing for obesity risk is available as part of consumer-based personal genetic testing services, but little is known about determinants of interest in this information. The Impact of Personal Genomics (PGen) Study is investigating the impact of consumer genetic testing in collaboration with two genetic testing companies through surveys with their customers prior to receiving their genetic results, and 2-3 weeks and 6 months after results disclosure. This analysis focused on baseline data to determine demographic and personal correlates of interest in genetic testing for obesity risk. Mean age of the 1170 participants was 47 years (SD=15.6) and they were 60.2% female, 89.5% white, 48.1% college educated, 49.1% had a family history of obesity , 55.4% were overweight/obese themselves (BMI>25) and 16.8% believed their chances of developing obesity were high. 41.0% reported that they were very interested in learning about their genetic risk of obesity. Logistic regression analysis revealed that individuals very interested in genetic testing for obesity were significantly more likely to be younger (p = .003), female (p < .001), have a family history of obesity (p < .001), be overweight/obese (p < .001) and perceive themselves at higher genetic risk of obesity (p < .001). There were no significant associations with education or ethnicity. After adjusting for elements that would be expected to motivate predictive testing (family history and perceived risk), we demonstrate that persons already overweight/obese are still motivated to learn about their genetic risk for obesity, perhaps because of its perceived explanatory value.
Social and behavioral sciences
Describe who is interested in genetic testing for obesity risk
Discuss possible reasons why affected individuals may be interested in obesity risk testing
Keyword(s): Genetics, Risk Communication
Presenting author's disclosure statement:
Qualified on the content I am responsible for because: I am currently undertaking a PhD investigating the psychological and behavioural effects of genetic test feedback for obesity risk. As part of my programme I have conducted a series of qualitative and quantitative studies on the topic, and I am aiming at becoming a specialist in the area of personalized genetic test feedback.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines,
and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed
in my presentation.