Exposure-response relationship between the number of anal sex partners and prevalent HIV, HSV-2 and syphilis infections among men who have sex with men
Methods: A cross-sectional survey was conducted among MSM having anal sex activities in the past six months in Shanghai from April 2008 to September 2009. A generalized linear mixed model with negative binomial distribution was used to examine the fixed effects. Exposure-response relationships were fitted by exponential curves.
Results: Among 1072 participants whose average age was 28.2(±8, range of 18-66) years, less than half (43%) persisted in condom use, the majority (60%) were self-identified homosexuals and approximately one-third (36%) were bisexuals. The prevalence of HSV-2, HIV, current syphilis and co-infections were 10.4%, 7.8%, 7.4% and 3.9%, respectively. A greater number of sex partners was associated with higher income), lower education level and commercial sex activity. In those without persistent condom use, a significant and accelerated increase in sexually transmitted infections (STIs) prevalence was associated with an increase in the number of sex partners. The prevalence of HSV-2 (25.6% - 30.1%), syphilis (23.0% - 27.7%) and HIV (21.5% - 25.7%) was very high while MSM had over 20 sex partners with unprotected anal intercourse in the past six months. However, the exposure-response relationships didn't exist in those using condom persistently.
Conclusion: Having multiple sex partners without persistent condom use is common among MSM in Shanghai, which is leading to the epidemic of HIV, HSV-2 and syphilis. It provides an evidence to develop effective intervention strategies for STIs prevention among MSM.
Learning Areas:Biostatistics, economics
Social and behavioral sciences
Identify the exposure-response relationships between the number of anal sex partners and the prevalence HIV, HSV-2 and syphilis infections
Keyword(s): Sexual Risk Behavior, Gay
Qualified on the content I am responsible for because: I have been worked in the epidemiology and biostatistics field for over 10 years. My scientific interests focus on apply the epidemiological and biostatistical methods to improve public health.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.