Online Program

A randomized trial to increase acceptance of childhood vaccines by vaccine-hesitant parents

Monday, November 4, 2013 : 2:50 p.m. - 3:10 p.m.

S. Elizabeth Williams, MD, MPH, Department of Pediatrics, Vanderbilt University Medical School, Nashville, TN
Increasing numbers of parents delay or refuse one or more of the recommended childhood vaccines. Strategies are needed to provide accurate and effective information to counter this trend. To perform a cluster randomized trial of an educational intervention for vaccine-hesitant parents in the outpatient clinic setting. Two primary care sites were randomized to provide families with either usual care or a brief video-based educational intervention addressing common concerns of vaccine-hesitant parents. Parents were approached at their child's 2 week well visit and eligible if performance on the Parent Attitudes about Childhood Vaccines (PACV) survey suggested vaccine-hesitancy (score ≥ 25). At 2 months, PACV surveys were completed again and vaccination status was collected at 12 weeks. The difference in PACV scores at screening and 2 months, and the proportion of on-time vaccination, was compared between groups. Four hundred and fifty-four parents were approached and 369 (81.3%) consented to screening; 132 had PACV scores ≥ 25 and were randomized (67 in the control group [mean PACV score 36.6] and 55 in the intervention group [mean PACV score 40]). The intervention group had a significant decrease in PACV score at two months compared to the control group (median difference= - 6.7, p=.049). This finding remained significant after adjustment for baseline PACV score, race/ethnicity, and income (p=.044). We found no difference in the on-time receipt of vaccines at 12 weeks. An intervention to improve parental attitudes regarding childhood vaccines for vaccine-hesitant parents was associated with a modest but significant increase in measured vaccine acceptance.

Learning Areas:

Administer health education strategies, interventions and programs
Communication and informatics
Implementation of health education strategies, interventions and programs
Public health or related education
Social and behavioral sciences

Learning Objectives:
Describe a new method for impacting attitudes of vaccine-hesitant parents regarding childhood vaccines.

Keyword(s): Immunizations, Health Behavior

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am first author and conducted the study
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.