141st APHA Annual Meeting

In This section

285324
Oral and pharyngeal cancer trends in Pennsylvania: 1999-2008

Monday, November 4, 2013

Amit Chattopadhyay, PhD, FFPH-RCPUK, MPH, CPH, MDS, BDS, PGDHHM, PGDMLS, DipGlobalEthics, GCertID, GCertPHO, DipJourn, MACE , Office of the Director, Office of Science Policy and Analysis, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD
Andres Pinto, DMD MPH , Oral Medicine and Community Oral Health, University of Pennsylvania, School of Dental Medicine, Philadelphia, PA
BACKGROUND: Oral and pharyngeal cancers (OPC) have dire prognoses due to late detection. Pennsylvania OPC statistics are not reported in the published literature (PubMed). Objectives: To assess OPC incidence and mortality rates and trends in Pennsylvania (1999-2008) compared to national rates. METHODS: The United States Cancer Statistics and Pennsylvania Cancer Registry data (from CDC Wonder) were used to assess OPC incidence and mortality rates and to analyze time trends and disparities across gender and racial-ethnic groups. The differences between rates were tested employing a Z-statistic and monotonic time-trend was tested by linear regression and Mann-Kendall's tau. RESULTS: In Pennsylvania, cumulative age adjusted rates [2008, per 100,000 (95% CI)] were as follows: Incidence: [Overall 11.2 (10.7-11.8)]; [Men 16.5 (15.5-17.5)]; [Women 6.7 (6.2-7.3)]; [Whites 11.1 (10.6-12.7)]; [African-Americans 10.4 (8.7-13.3)]. Trend for increasing incidence over study period was statistically significant (p<0.001). Mortality (trend p=0.26): [Overall 2.4 (2.2-2.7)]; [Men 3.7 (3.2-4.1)]; [Women 1.5 (1.2-1.7)]; [Whites 2.3 (2.1-3.6)]; [African-Americans 3.3 (2.4-5.4)]. In the U.S., overall cumulative age adjusted rates for year 2008 were as follows: Incidence: [Overall 11.2 (11.1-11.3)]; and Mortality: [Overall: 2.5 (2.4-2.5)]. Annual incidence and mortality rates in PA were slightly lower than US rates. Compared to Pennsylvania, Philadelphia-Camden-Wilmington (MSA) OPC incidence rates were higher, mortality lower although annual percent changes in the MSA were variable. CONCLUSION: Pennsylvania and national OPC incidence rates are similar. Significant gender-based disparities in incidence/ mortality are evident. The MSA has higher incidence/ mortality rates compared to Pennsylvania and national figures. Acknowledgement: This study is supported by NIH.

Learning Areas:
Epidemiology
Public health or related research

Learning Objectives:
Describe oro-pharyngeal cancer burden of Pennsylvania and the US. Discuss & describe trends in oro-pharyngeal cancer burden of Pennsylvania. Discuss & describe trends in disparities in incidence and mortality of oro-pharyngeal cancer burden of Pennsylvania. Assess other factors that impact incidence and mortality of oro-pharyngeal cancer burden of Pennsylvania.

Keywords: Cancer, Epidemiology

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I conducted the study
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.