Online Program

Analysis of Risk Factors of Second Time Infection of Hand-Foot-and-Mouth Disease in China

Sunday, November 1, 2015

Jun Xu, School of Public Health, University of North Texas Health science center, Fort Worth, TX
Jing Zhao, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX
Ziming Wang, Jiangtai Community Heath Service Center of Chaoyang District, Beijing, Beijing, China
Jiayi Xu, School of Medicine, Hebei Medical University, China, Shijiazhuang, China
Background Hand Foot Mouth Disease (HFMD) is one of the communicable diseases with high incidence in preschool aged children (kindergarten and scattered children) in China. HFMD can repeatedly infect children, but risk factors of repeated infection have not been reported by researchers.

Objective To explore the risk factors of second time infection of HFMD among preschool and scattered children in Jiang Tai County, Chaoyang district, Beijing, China     

Resource The surveillance data of HFMD was obtained through China National Diseases Reporting Information System and the social and behavioral information was provided by local health service center. There were 694 cases in total from 2008 to 2013.

Statistical Methods Bivariate analysis was conducted between whether had second time infection and potential risk factors of HFMD. The multivariable analysis was conducted using Logistic regression. Backward elimination method was used to select variables.

Results For the binary analysis, whether washing hand after outdoor activity every time was significantly associated with second time infection. For the multivariable analysis, three variables were stayed in the model, which were whether washing hand after outdoor activity every time, whether washing hand after stooling and before eating and the style of children (school, kindergarten or scattered). However, only the first variable was significant at 5% level, which means that children who did not wash hand after outdoor activity every time were 7.6 (95%CI: 1.28—45.44, p=0.026) times more likely to get HFMD again than children who did, controlling for the other two variables.

Conclusion The frequency and habit of washing hand (washing hand after outdoor activity every time) should be paid attention to prevent repeated infected with HFMD in children.

Learning Areas:

Protection of the public in relation to communicable diseases including prevention or control

Learning Objectives:
Identify the risk factors of second time infection of Hand-Foot-and-Mouth Disease among preschool and scattered children.

Keyword(s): Child Health, Epidemiology

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am a principal investigator to this research. I used 5 years and more to fellow the cohort.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.