Exposure to environmental tobacco smoke and lung cancer in Chinese populations: A meta-analysis of 30 studies
Methods We conducted a meta-analysis of 30 studies involving a total of 7,318 cases and 14,139 controls. The pooled odds ratio (OR) and its 95% confidence interval (CI) were calculated using both fixed- and random-effects models. Tests of heterogeneity and stratified analyses were performed by study design, study size, location, publication date, and language of publication.
Results The overall pooled OR for the association between exposure to ETS and lung cancer risk among Chinese individuals was 1.49 (95% CI: 1.32-1.68) using the random-effects model. The estimate of association was higher for studies published in Chinese (OR=1.83, 95% CI: 1.39-2.41) than for studies published in English (OR=1.40, 95% CI: 1.23-1.61).
Conclusion The pooled ORs from comparable meta-analyses of studies conducted among Western populations typically do not exceed 1.4. Therefore, exposure to ETS might be a stronger risk factor for lung cancer in China than in Western countries. China will benefit greatly from stronger public health policies and health education efforts aimed toward reducing its people’s exposure to tobacco smoke.
Learning Areas:Environmental health sciences
Assess the association between environmental tobacco smoke exposure and lung cancer risk in Chinese populations.
Keyword(s): Cancer, Tobacco Control
Qualified on the content I am responsible for because: I am writing a doctoral dissertation on the epidemiology of environmental tobacco smoke exposure and lung cancer. I have published a paper on this topic as first author in the International Journal of Cancer.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.