Online Program

Incidence of HIV at first PCR testing among infants born to HIV positive mothers in Kumasi

Sunday, November 1, 2015

Dennis O. Laryea, MD MPH MGCP, Public Health Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana
Stephen Ayisi Addo, MD MPH, National AIDS/STI Control Programme, Accra, Ghana
Benedicta Bonsu, MD, Family Medicine Directorate, Komfo Anokye Teaching Hospital, Kumasi, Ghana
Yaw Amoako, BSc MD FWACP, Directorate of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana
Preventing mother-to-child transmission of HIV is a major global strategy to reduce the incidence of new infections. Serological confirmation of HIV in children born to HIV positive mothers required testing at 18 months of age and was associated with parental anxiety and high risk of drop-out.  The Early Infant Diagnosis (EID) of HIV using Polymerase Chain Reaction has resulted in a major shift in diagnosing HIV in infants and provided an opportunity to offer comprehensive care to the HIV-exposed child.  We analyze EID the Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana from 2011 to 2013.

Twenty-two (4.17%) infants were confirmed HIV positive by PCR out of a total of 527 HIV-exposed babies. The proportion of HIV positive infants was uniformly distributed by sex, 4.21% males and females 4.24% with no statistically significant difference between the two groups. About a third of children born to mothers not on any form of treatment were HIV positive compared with 2.5% and 0.6% for children born to women on HAART and ARV Prophylaxis respectively. Children delivered in KATH were less likely to be HIV positive compared with those delivered outside KATH (OR= 0.23; p= 0.03). No association was found between the mode of delivery and HIV status of infant.  

Children born to women on antiretrovirals during pregnancy are less likely to be HIV positive. Achieving zero infections in children born to HIV positive mothers is possible. There are lessons to be learnt from the KATH programme to help achieve this.

Learning Areas:

Public health or related organizational policy, standards, or other guidelines
Public health or related research

Learning Objectives:
Analyze the outcomes of the Early Infant Diagnosis of HIV program at the Komfo Anokye Teaching Hospital in Kumasi, Ghana

Keyword(s): HIV Interventions, Practice-Based Research

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I work as a Reproductive and Child Health specialist with Public Health Unit and also as the Coordinator of HIV activities in the hospital. I supervise activities at the Prevention of Mother-to-Child Transmission of HIV clinic and was personally involved in the collection and analysis of data presented in this abstract.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.