Exploring Health Disparities in Asian and Pacific Islanders in Pediatric Heart Transplantation in the US
METHODS: Patients ≤25 years of age listed for isolated HT since 1986 were identified using OPTN data. Race/ethnicity was analyzed as reported by centers. Survival was estimated using the Kaplan-Meier method. Waitlist mortality was defined as waitlist removal due to death or clinical deterioration.
RESULTS: Of 15,686 patients listed for HT, 517 (3.3%) were API, including 458 (2.9%) Asian and 59 (0.4%) Pacific Islander (PI) patients. API patients were more similar to whites at transplant listing than blacks/Hispanics, although APIs were more likely to have blood type B and normal renal function than non-API patients. Overall, API and non-API patients had similar unadjusted waitlist mortality. Of 10,181 patients transplanted, 368 (3.6%) were API, including 329 (3.2%) Asian and 39 (0.4%) PI patients. Overall post-transplant survival was similar for API and non-API patients, however, Asians had a trend toward longer survival (similar to whites) compared to PIs (similar to blacks/Hispanics).
CONCLUSION: Overall waitlist and post-heart transplant survival for API pediatric patients is similar to other racial/ethnic groups, however, PIs have a trend toward shorter post-transplant survival compared to Asians. Further research is warranted to understand racial/ethnic disparities in post-transplant survival for Asians and Pacific Islanders.
Learning Areas:Clinical medicine applied in public health
Describe waitlist and post- heart transplantation outcomes for Asian and Pacific Islander pediatric patients. Compare waitlist and post-heart transplantation outcomes for Asian and Pacific Islanders versus other racial/ethnic groups.
Keyword(s): Health Disparities/Inequities, Asian and Pacific Islanders
Qualified on the content I am responsible for because: I am the clinical research coordinator for the investigator-initiated and industry-sponsored studies in the Department of Pediatric Cardiology at Lucile Packard Childrenâs Hospital- Stanford University. I have a MPH, with a focus in Community Health and Education, and have over five years of research experience. My public health research interests include health disparities and inequities among underserved populations and community-based participatory research.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.