Prevalence and Correlates of Coronary Artery Disease among community-dwelling Young Adults in the United States
Methods: We abstracted data from the National Health and Nutrition Examination Survey of 9,802 adults aged 20-44 years, from 2005-2012. Age-adjusted population-based CAD prevalence rates based on self-reports of prior diagnosis with CAD or myocardial infarction were computed. Multivariable logistic regression was utilized to examine the association between CAD and: sociodemographic variables, history of cocaine and marijuana use, smoking history, secondhand smoking, BMI, high density lipoprotein (HDL) cholesterol, hypertension, and diabetes mellitus. Survey weights were applied, and odds ratios (OR), and confidence intervals (CI) were computed.
Results: The age-adjusted prevalence of CAD among those aged 20-44 years was less than 1% (0.79%; 95% CI 0.56-1.02) and was statistically non-different between males and females. In multivariable analysis, increased odds of CAD were seen with: being underweight (OR: 6.98; 95% CI 1.17-38.24); diabetes mellitus (OR: 5.28; 95% CI 1.45-19.21); hypertension (OR: 3.89; 95% CI 1.24-12.18); a life-time smoking history of at least 100 cigarettes (OR: 3.10; 95% CI 1.29, 7.39); and low HDL (OR: 2.95; 95% CI 1.25-6.97).
Conclusion: In addition to the traditional risk factors, CAD may be associated with being underweight, albeit among those aged 20-44 years. Prospective studies are needed to clarify the nature of the relationship between CAD and non-traditional risk factors such as being underweight in this age group.
Learning Areas:Chronic disease management and prevention
Clinical medicine applied in public health
Describe the burden and correlates of coronary artery disease in young adults in the United States
Keyword(s): Heart Disease, Youth
Qualified on the content I am responsible for because: I am a physician with research interests in the prevention and control coronary artery disease and stroke in special populations such as the young and ethnic minorities. In addition, I am experienced in the analysis of survey and large administrative data sets.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.