Association between obesity and high-risk human papillomavirus infection among women in the United States, 2009-2010
methods: Non-pregnant women ages 18-59 (n=1,921) who participated in the 2009-2010 National Health and Nutrition Examination Survey (NHANES) were studied. HPV status was determined by self-collected vaginal specimens. Obesity was defined as body mass index (BMI) ≥30 kg/m2or waist circumference ≥ 88cm.
results: Compared to normal-weight women, obese women were significantly more likely to be non-Hispanic black, 41-50 years old, have an education of high school grad or less, have an annual household income ≤$24,999, and be HSV2 seropositive (p<.0001). Women with HR-HPV were significantly more likely to be non-Hispanic black, 18-30 years old, have a lower education level, have an annual household income ≤$24,999, be HSV2 seropositive, have a history of risky sexual behaviors and sexually transmitted disease, and, smoke cigarettes compared to women who were negative for HR-HPV (p<.0001). There was no significant relationship between obesity and HR-HPV infection, except among Mexican Americans for which class I obesity (OR: .352; 95% CI: .177-.699) and having a waist circumference ≥88cm (OR: .600; 95% CI .367-.980) were protective factors against HR-HPV.
discussion/conclusions: This study suggests that there is only an association between obesity and HR-HPV among Mexican Americans. Further research is needed to determine if using other measures of adiposity, such as body fat percentage, may better examine obesity within other minority populations.
Learning Areas:Public health or related education
Public health or related research
Social and behavioral sciences
Assess whether there is a relationship between obesity and high-risk human papillomavirus (HR-HPV) infection. Assess the relationship between obesity and HR-HPV infection, when stratified by race/ethnicity. Identify whether other measures of obesity (i.e. weight and waist circumference) are associated with HR-HPV, when stratified by race/ethnicity.
Keyword(s): Obesity, STDs/STI
Qualified on the content I am responsible for because: I am a Master of Public Health Candidate at Morehouse School of Medicine who has studied in the area of women's health for six years. Additionally, I have developed a vigorous interest in STDs/STIs and have worked in this area specifically with at-risk youth throughout the country. Furthermore, I have presented at the Howard University Research Symposium in Washington, D.C. This interest has allowed me to become the principal investigator of this current research study.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.