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Effect of Highly Active Antiretroviral Therapy on Risky Sexual Behaviors Among HIV Positive Individuals: A Systematic Review
methods: A systematic review was conducted according to PRISMA guidelines using MEDLINE and five other databases for studies published between 2004 and 2013 without any language limits. Screening, data extraction and quality rating was conducted independently by two reviewers.
results: 49 articles were screened out of which 6 studies examined for RSB among HIV+ individuals while on HAART, and 13 examined the impact of ART. Although both sexes were less likely to engage in unprotected sex after receiving HAART, the decrease was greater for men (AOR: 0.33 [95% CI: 0.24–0.44]; p<0.0001) than for women (AOR: 0.71 [95% CI: 0.59–0.86]; p=0.0005). In comparison to HAART, those on preventive therapy were more likely to report multiple sex partners and having unprotected sex with regular partner. Individuals on ART, were less likely to have unprotected sex with HIV- or unknown HIV-status partners.
conclusions: The findings from our review suggest that there is no increase; and in RSB and in most cases, there was actually a decrease in sexual risk behaviors among HIV positive individuals post-HAART.
Learning Areas:
Chronic disease management and preventionEpidemiology
Implementation of health education strategies, interventions and programs
Public health or related education
Public health or related research
Learning Objectives:
Evaluate the evidence if there is an increase in risky sexual behaviors among HIV+ individuals receiving Highly Active Antiretroviral Therapy or Antiretroviral Therapy.
Keyword(s): HIV/AIDS
Qualified on the content I am responsible for because: I am a second year PhD student whom possess sufficient knowledge in the HIV/AIDS area. My background consist of identifying and recruiting high risk-women of reproductive age, pregnant women who are at risk of HIV infection, are HIV positive and/or substance abusers not receiving appropriate prenatal care among disadvantaged communities in Broward County Florida, providing education and counseling on HIV, STDs, and Family Planning Topics, and conducting pregnancy and HIV testing for high risk women.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.