In April 2011, the U.S. Department of Health and Human Services' (HHS) Office of Minority Health (OMH) established the National Partnership for Action to End Health Disparities (NPA) to increase the effectiveness of efforts to eliminate health disparities by coordinating partners, leaders, and stakeholders committed to action. An evaluation goal of the NPA is to determine the extent to which the initiative, by creating multi-sector partnerships across different levels (federal, national, regional, state, and local), calls attention to social determinants of health, and informs and supports strategies to end racial and ethnic health disparities. The mixed-methods evaluation was designed to: (1) document the initiative's ongoing implementation and progress, (2) track successes and lessons learned, (3) provide insight regarding the components of the NPA that should be sustained or modified, and (4) discern the initiative's outcomes and best practices. This session will present key findings of the three-year process and outcome evaluation and describe the evolution of the NPA in terms of its membership base, priority areas, key activities, and influence at the community level. This session will discuss how the NPA as a multi-level strategy has been used to identify community health equity issues and strategies for addressing those health inequities. Vignettes will be presented that document the growing influence the NPA demonstrates at community, County, and State levels, as well as key partnerships that have been developed between NPA stakeholders and community-based and for-profit organizations throughout the country.