Background: Sexual violence is a public health crisis with 1 in 5 women and 1 in 16 men experiencing sexual assault in college. There is a need for holistic primary prevention interventions. Past research emphasizes life skills and social competency as approaches that address individuals within their ecological context. We use a participatory approach and the ADAPT-ITT model to assess student needs in relation to life skills and holistic self-care, followed by decisions on adapting a pre-existing web-based application (app). Methods: A diverse group of students and faculty/staff were recruited using flyers, announcements, and snowball sampling for focus group discussions (FGDs; 7 with students and 3 with faculty/staff). FGDs focused on the four domains of (1) interpersonal relationships, (2) sexual violence, (3) campus resources, and (4) diversity. A Student Advisory Board and Technical Expertise Group made final decisions on the content included in the app. Results: Preliminary analyses indicate participants recommend the following core domains: (1) broad focus on interpersonal relationships including those with roommates, faculty, friends, family, and sexual partners; (2) components of healthy relationships including communication, conflict management, negotiating, and empowerment; (3) identifying problems in relationships including misalignment of values, toxicity, or violence; and (4) resources that are inclusive to a diverse student body. Conclusions: The ADAPT-ITT model provided a useful framework to begin adapting a pre-existing app focused on life skills and holistic self-care. Participants were excited about the potential this app has to provide a wide breadth of information about healthy relationships to diverse students.