Living 2,285 miles from the nearest land mass, Native Hawaiians the indigenous peoples of Hawai‘i, developed a deep and knowledgeable relationship with the environment that made Native Hawaiians healthy and robust. With Western contact and the colonization policies that followed, pervasive health disparities exist today. Native Hawaiians have high rates of obesity-related diseases and tend to live in food deserts. In addition, Hawai‘i’s residents face the highest food costs in the U.S. as 90% of the food supply is imported. To address these issues, over 70 Native Hawaiian families have been engaged in building aquaponics systems in their backyards since 2010. Aquaponics utilizes a symbiotic relationship between fish and plants by effectively combining hydroponics (raising plants in water) and aquaculture (raising fish in tanks). To identify the impacts of these backyard aquaponics systems and suggestions for future direction, public health graduate students conducted in-depth interviews with 10 families. Participants reported that their aquaponics systems have increased their access to and intake of fresh fruits and vegetables, strengthened their family relationships, increased financial savings, and enhanced their sense of community connectedness as many shared their excess produce with their neighbors. Aquapponics also resonates with Native Hawaiian values of land stewardship. Participants asked for more technical assistance with maintaining the system as well as ongoing opportunities for participants to stay connected with one another. Backyard aquaponics may be a promising strategy for minority and indigenous communities to promote food access, self-sufficiency, and sustainability.