Background: The Realizing Educational Attainment and Careers in Healthcare (REACH) program design was developed based on a social determinants model and the experiences of a previous Nursing Workforce Diversity project that was effective in increasing the pre-nursing enrollment of diverse and disadvantaged students. The purpose of this Nursing Workforce Diversity project is to increase nursing progression and graduation rates and retention in practice for individuals who are from diverse and/or disadvantaged backgrounds (specifically individuals from racial/ethnic minorities under-represented among registered nurses). Description: The REACH program goals focus on four levels including: 1) Individual: Neutralize the impact of economic environmental factors that are barriers for diverse and disadvantaged populations to pursue a bachelor’s in nursing; 2) Group: Participants will bridge gaps within the social determinants framework to achieve progression and graduation; 3) Institutional: Broaden the cultural competence of nursing and other faculty on campus and; 4) Community: Expand the knowledge and skills of social determinants of health and cultural competence for nurses within the largest nursing employer in the community. Lessons Learned: Evidence-based, interdisciplinary, multi-level partnership models, and strategies that incorporate a social determinant framework guided the interventions and achievement of program goals to impact students, faculty, staff, and practicing nurses within the community. Implications/recommendations: A multi-level, multi-disciplinary approach to addressing the social determinants of health allows for successfully diversifying the nursing workforce. Ultimately, residents of the local community are better served by a diverse nursing workforce that is responsive to the variety of cultural needs of the population it serves.