Black women make up the second largest group affected by sexually transmitted infections (STIs). Most of these women have contracted these diseases through modes of heterosexual transmission, including orally and vaginally. However, some researchers believe that STI transmission via heterosexual anal sex has been largely overlooked due to under-reporting of anal sex behaviors. As receptive anal sex is the riskiest sexual behavior for HIV transmission, ignoring anal sex as a mechanism for other STI transmission may have dire effects on the sexual health of Black Americans. A sample of Black Americans (n = 1548) from the NSFG, 2013-2015 dataset, was utilized to assess anal sex practices, risk for sexually transmitted infections, and condom use. Univariate analysis were conducted to summarize the demographic characteristics, anal sex practices, condom use, and sexually transmitted infections testing and treatment of participants.Independent effects of demographic factors, anal sex practices, condom use, and sexually transmitted infection testing and treatment were estimated by constructing logistic regression models. Models were constructed to assess predictors of number of STI diagnoses. Binary logistic regressions were constructed to predict anal sex behavior among Black Americans. Odds ratios (ORs) and their corresponding 95% confidence intervals (CIs) were computed. Individuals who engaged in anal sex practices were found to be at greater risk for a STI diagnosis, than those individuals who did not report having engaged in anal sex. Additionally, most individuals who engaged in anal sex did not use condoms during their last anal sex encounter. Individuals were more likely to have used condoms during their last vaginal sex encounter than during their last anal sex encounter. Findings from this study point to an increased risk of STI transmission for individuals who participate in anal sex. As anal sex places individuals at a higher risk for a STI diagnosis, public health professionals should extend sexual health messaging surrounding anal sex to include heterosexual individuals. Additionally, reducing the stigma of anal sex may be important for reducing STI transmission. Including anal sex in sexual health questionnaires for self-identifying heterosexual individuals may also be an important step toward reducing STI diagnoses among Black Americans.