Background: Age-adjusted mortality among low-income people living with HIV (PLWH) participating in the New York City (NYC) Ryan White Part A (RWPA) program has consistently exceeded that among NYC PLWH overall. Evaluating client characteristics and service utilization patterns associated with mortality in RWPA can facilitate focused service delivery efforts and earlier identification of clients at risk of preventable mortality. Methods: This analysis included clients who left the RWPA program 2013-2015 and were served by a long-term RWPA service category in the year prior. Sociodemographic, clinical, and service utilization characteristics were included in a logistic regression model to compare those who died and those who left the program for other reasons. Results: Of 8,123 clients, 767 were deceased. Statistically significant associations with death included diagnoses of hepatitis C (p<.01), cancer (p<.01), diabetes (p<.01), HIV diagnosis prior to 2006 (p<.01), and lack of viral suppression at latest test 3-15 months prior to exit (p<.01). In addition, clients who received services from care coordination (CC) (p<.01) or food and nutrition (FN) (p<.01) programs, as well as those receiving multiple long-term RWPA services (p=.03), were significantly more likely to have died. Conclusions: In our cohort of clients who had recently exited RWPA services, death was associated with specific program use (CC and FN) and engagement with multiple services as well as co-morbidities, unsuppressed viral loads, or earlier diagnosis years. The utilization of multiple service categories simultaneously indicates complex needs requiring cross-program coordination. Additional understanding of these findings may allow critical intervention for mortality prevention.