We will describe a family-centered citizen science project to empower high school students and their teachers to address environmental concerns about radon exposure in homes in rural Appalachian Kentucky. Community members expressed concerns about radon exposure given the increase in fracking, the underlying bedrock geology, high smoking prevalence and secondhand smoke exposure, and high rates of lung cancer in the region. Although 85% of lung cancer cases are caused by cigarette smoking and SHS, radon exposure accounts for 10-15% of lung cancer cases. We adapted a home radon testing toolkit designed for classroom education with youth citizen scientists. The radon toolkit includes information about radon, how to test, and how to interpret the findings. The classroom training included: (1) human subjects training for youth to be added to the IRB-approved study protocol; (2) information on the health effects of radon; (3) review of the science protocol and instructions for deploying the Alpha Energy test kit in their home (location, duration of testing, when to return) to ensure rigorous data collection; and (4) considerations for report-back if home radon levels are high (> 4.0 pCi/L). After classroom training, youth citizen scientists explained the study to their parents and obtained informed consent. If radon levels were high, the trained youth citizen scientists discussed options with their parents, in consultation with the academic team. For homeowners who chose to mitigate, we provided a voucher to pay for $1,000 of the total cost to cover approximately half the cost of radon mitigation. We validated the home radon toolkit at the Kentucky sites using in situ soil radon gas measurements, and evaluated the usability and feasibility of the toolkit for radon sampling with high school students and their families. We will share results and benefits of the family-centered home radon testing toolkit in rural Appalachia.