Disasters are becoming more common and challenge national and global resiliency and response efforts, creating an increased interest in disaster research to strengthen preparedness, response, and recovery following disasters. As more worker populations are exposed to disasters through response and recovery efforts, there is interest in studying the longitudinal health effects associated with disaster response. The NIH Disaster Research Response (DR2) Project aims to reduce the time required to deploy a “research response” by creating a disaster research system consisting of coordinated environmental health disaster research data collection tools and trained research responders. One key aspect of the DR2 project is a “pre-approved” disaster research protocol named RAPIDD (Rapid Acquisition of Pre- and Post-Incident Disaster Data), which contains tools for exploring occupational injury and risk in disaster responders. However, having the data collection tools is just one component of the program. Disasters are often complex and present unique circumstances that may require a nuanced research protocol review process. Institutional Review Boards (IRBs) are now being asked to review research protocols aimed at assessing health risks, exposures and outcomes of disaster responders and their communities; however, few IRBs have significant experience reviewing disaster research protocols. Therefore robust training and infrastructure are needed to support IRB preparedness for rapidly implementing disaster research protocols. As national leaders of disaster research, the NIEHS DR2 Program recognized the need to prepare and train IRBs to conduct ethical reviews of disaster-related research. We have developed disaster-related IRB curricula and tools for conducting ethical reviews for timely research following disasters. These materials have been vetted through IRB disaster research training sessions held with the National Institute for Occupational Safety and Health (NIOSH) and others, providing regulatory guidance and contextual considerations for IRB review. This presentation describes the training materials and how to make use of DR2 resources.