Certain malignancies may be linked with long-term, low-dose exposures from radiation and other environmental sources. CT Tumor Registry incidence data for 1976 to 1995 on 7,831 leukemias, 3,059 multiple myelomas and 2,805 thyroid cancers were examined for geographic variation across the State's 169 towns using a spatial scan statistic to detect and evaluate the statistical significance of incidence rate differences at various locations relative to statewide experiences. No significant geographic variation of acute leukemia in either children or adults was measured. Significant, but modest, elevation of adult chronic lymphocytic leukemia was found in Central Connecticut (RR=1.16, p=0.003). Incidence of multiple myeloma was significantly greater within another area of North Central Connecticut (RR=1.32, p=0.008). These findings will be considered in relation to their proximity to sites of energy production and distribution and other environmental hazards around the State.
Learning Objectives: Describe geographic differences in cancer rates Illustrate use of spatial scan statistic to quantify and test significance of rate differences
Keywords: Cancer, Surveillance
Presenting author's disclosure statement:
Organization/institution whose products or services will be discussed: Caliper Corp (Maptitude software)
NCI (SaTScan software)
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.