3259.0: Monday, November 13, 2000 - 9:30 PM

Abstract #11104

Estimation of a preference-based measure of health from the SF-36

John E Brazier, PhD1, Jennifer Roberts, PhD1, Mark Deverill1, Barbara Gandek2, and John Ware, PhD2. (1) School of Health and Related Research, The University of Sheffield, Regent Court, 30 Regent Street, Sheffield, S1 4AD, United Kingdom, 0114 2220726, J.E.Brazier@sheffield.ac.uk, (2) Health Assessment Laboratory, New England Medical Centre, 15 Court Square, Suite 400, Boston, MA 02108

This paper reports on the findings of a study to derive a preference-based algorithm for estimating a single index measure from the SF-36 for use in economic evaluation and population health surveys

The SF-36 was revised into a six dimensional health state classification called the SF-6D. A sample of 250 states defined by the SF-6D have been valued by a representative sample of 781 members of the UK general population, using standard gamble. The overall aim is to construct a model for predicting health state valuations for all 18,000 states defined by the SF-6D. The econometric modelling must cope with the hierarchical nature of the data (each individual values 6 health states) and its skewed distribution. The models have produced robust estimates of the 'main effects' and, in general, the results support the ordinality of the SF-6D scales. There are problems modelling interaction effects and we find little influence from personal characteristics. Random effects and mean models provide very similar results. The pain, mental health and physical functioning dimensions are the most important in determining the value assigned to a state. The models predict 70% of health state values to within |0.10| and 40% to within |0.05|. The choice of models for applying to SF-36 data and the implications for research will be discussed.

Learning Objectives: Participants should be able to 1) describe the methodology for obtaining preference information for the SF-36 and 2) recognise the application of the results in the conduct of economic evaluations

Presenting author's disclosure statement:
Organization/institution whose products or services will be discussed: None
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.

The 128th Annual Meeting of APHA