4304.0: Tuesday, November 14, 2000 - 4:55 PM

Abstract #18407

The Statistical Analysis of Cost-Effectiveness Data from Clinical Trials

Andrew Willan, PhD, McMaster University, , willana@fhs.csu.mcmaster.ca

There are three approaches to health economic evaluation for comparing two therapies. These are (i) cost imization, in which one assumes or observes no ifference in effectiveness; (ii) incremental cost-effectiveness; and, (iii) incremental net benefit. The latter can be expressed either in units of effectiveness or costs. When analyzing patient-level data from a clinical trial, expressing mental net benefit in units of cost allows the vestigator to examine all three approaches in a single graph, complete with the corresponding statistical inferences. Furthermore, if costs and effectiveness are not censored, this can be achieved using common two-sample statistical procedures. Procedures for making inferences about incremental net benefit, when the willingness-to-accept compensation to forgo current health benefit is greater than the willingness-to-pay to receive additional health benefit, will be discussed.

Regression Analysis of Censored Medical Cost Data

Learning Objectives: N/A

Keywords: Clinical Trails, Cost Issues

Presenting author's disclosure statement:
Organization/institution whose products or services will be discussed: None
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.

The 128th Annual Meeting of APHA