4215.0: Tuesday, November 14, 2000: 2:30 PM-4:00 PM

Challenges to implementing public health models of mental health intervention research: lessons from the field

NIMH is currently sponsoring several large scale effectiveness trials in which the rules of traditional RCT methodologies are confronted by the goals of public health. The purpose of this session is to debate how traditional RCT methodology needs to be revised when moving into large scale, long term, public health oriented mental health intervention trials. The discussion uses as a backdrop four NIMH-funded intervention studies: PROSPECT (targeting late life suicide risk and depression in primary care); STEP-BD (targeting treatment effectiveness in bipolar disorder); STAR*D (targeting treatment resistant depression); and CATIE (targeting psychotic disorders). Lead investigators from each study will discuss issues such as randomization, sampling, masking, leaking of treatment between groups, treatment as usual, diagnostics, monitoring for fidelity of treatment delivery, special methods to enhance adherence and compliance, incorporating patient and clinician preferences into these designs, and implications of using algorithmic strategies as opposed to single, discrete treatments
Learning Objectives:
Discussant(s):Martha L. Bruce, PhD,, MPH
Barry D. Lebowitz, PhD
Robert A. Rosenheck, MD
Philip W. Lavori, PhD
Maurizio Fava, MD
Gary S. Sachs, MD
Organizer(s):Martha L. Bruce, MPH, PhD
Sponsor:Mental Health
Cosponsors:Epidemiology; Social Work

The 128th Annual Meeting of APHA