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The 130th Annual Meeting of APHA |
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The 130th Annual Meeting of APHA |
Hiroshi Yanagawa, MD1, Yosikazu Nakamura, MD, MPH2, and Mayumi Yashiro2. (1) Saitama Prefectural University, 820 Sannnomiya, Koshigaya-shi, Saitama-kenn, 343-8540, Japan, +81-489-73-4806, yanagawa-hiroshi@spu.ac.jp, (2) Department of Public Health, Jichi Medical School, 3311 Yakushiji, Minamikawachi-machi, Tochigi-ken, 329-0498, Japan
Background: Since 1970, 16 nationwide epidemiologic incidence surveys of Kawasaki disease have been carried out successively in every two year-period with equivalent criteria in Japan. The diagnostic criteria of KD in this series was either the patients with at least 5 items of 6 principal symptoms or with at least 4 items when coronary aneurysm is recognized by two dimensional echo cardiography or coronary angiography. Objective: The purpose of this study is to describe epidemiologic pictures of patients reported through the surveys, especially yearly trend of the incidence rates in Japan over 30 years since 1970. Methods: Sixteen nationwide epidemiological surveys have been conducted to all the pediatric departments of the hospitals with more than 100 beds throughout Japan in every two-year period. Results: Total number of patients occurred by the end of December 2000 were 168,394 (Males: 97,700, Females: 70,694, Male/female ratio=1.38). The number of cases increased straightly year by year with three outbreaks in 1979, 1982 and 1986. The incidence rates were higher in males and in younger age groups of one year or less. The fatality rates decreased from 1% in 1974 to 0.05% in 2000. The incidence rates per 100,000 children of < 5 years old were 113.5 in 1999 and 134.2 in 2000. [Preliminary tabulation as of June 30, 2001] Conclusions: Thee incidence rate is steadily increasing year by year in Japan. The patterns of descriptive epidemiology, such as seasonal variation and cyclic changes of the occurrence supported the infectious agent as an etiology.
Learning Objectives:
Keywords: Epidemiology, Disease Management
Related Web page: www.KAWASAKI-DISEASE.ORG/
Presenting author's disclosure statement:
Organization/institution whose products or services will be discussed: CDC,state health department,university and children's hospitals
I do not have any significant financial interest/arrangement or affiliation with any organization/institution whose products or services are being discussed in this session.