APHA
Back to Annual Meeting
APHA 2006 APHA
Back to Annual Meeting
APHA Scientific Session and Event Listing

[ Recorded presentation ] Recorded presentation

Prevalence of congenital cardiovascular malformations varies between Whites, Blacks, and Hispanics

Tania Mangones, MD1, Amitoz Manhas1, Paul Visintainer, PhD2, Cheryl Hunter-Grant, MSW1, and Heather Brumberg, MD, MPH1. (1) Division of Neonatology, Westchester Medical Center at NY Medical College, 95 Grasslands Rd, Valhalla, NY 10595, 9144938491, taniam1118@yahoo.com, (2) Epidemiology, NY Medical College, 95 Grasslands Rd, Valhalla, NY 10595

Background: The prevalence of congenital cardiovascular malformations (CCVMs) has been found to differ between Whites and Blacks. However, little attention has focused on Hispanic population rates. Objective: To determine the prevalence of CCVMs in NYS Hudson Valley Region (HVR) by race. Methods: NYS Vital Statistics and Congential Malformations Registry data obtained by race from 1992-2001 across 7 counties of HVR. Poisson regression, adjusting for population size, analysis done of relative risks (RR). Results: There were 3,075 CCVMs in 2,303 children from a birth population of 297,606. For all CCVMs, 14.4 malformations/1000 live births in Non-Hispanic Whites (NHW, 12.8/1000 in Non-Hispanic Blacks (NHB), 8.8/1000 in Hispanics and 8.4/1000 in Others. The risk of all CCVMs was lower in NHB [RR=0.89, 95%CI 0.80-0.99], Hispanics [RR=0.61, 95%CI 0.54-0.68], and Others [RR=0.58, 95%CI 0.50-0.69]compared to NHW. The risk of Tetralogy of Fallot(TOF) in Hispanics [RR=0.31, 95%CI 0.14-0.67]was significantly lower than NHW, but not in NHB and Others. The risk of Great Vessel anomalies relative to NHW was lower in NHB [RR=0.48, 95%CI 0.24-0.95] and Hispanics [RR=0.33, 95%CI 0.16-0.67] but not in Others. The risk of VSD compared to NHW was lower in NHB [RR=0.60, 95%CI 0.48-0.75], Hispanics [RR=0.63, 95%CI 0.52-0.77], and Others [RR=0.65, 95%CI 0.49-0.86]. Conclusions: In HVR all CCVMs and specific anomalies such as TOF have the highest prevalence in Whites with Hispanics consistently maintaining a lower risk. These data suggest a targeted approach for diagnosis and treatment.

Learning Objectives:

Keywords: Epidemiology, Ethnicity

Presenting author's disclosure statement:

Any relevant financial relationships? No

[ Recorded presentation ] Recorded presentation

Epidemiological Analysis in MCH - Beyond the Basics

The 134th Annual Meeting & Exposition (November 4-8, 2006) of APHA