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APHA Scientific Session and Event Listing

Recorded presentation

H. Dean Hosgood, MPH¹, Dalsu Baris, MD, PhD², Shelia Zahm, ScD², and Tongzhang Zheng, BMed, ScD, ScM¹. (1) Environmental Health Sciences, Yale University School of Public Health, 60 College St, P.O. Box 208034, New Haven, CT 06520-8034, 203.215.3275, dean.hosgood@yale.edu, (2) Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, MSC 7242, Bethesda, MD 20892-7335

We used data from a population-based case-control study conducted among women in Connecticut to examine the impact of diet on risk of multiple myeloma (MM). This study included 179 MM cases (87.2% whites and 12.8% blacks) aged 21-84 years, diagnosed between 1996 and 2002, and 691 population controls (96.4% whites and 3.6% blacks). A food frequency questionnaire was used to assess the subjects' frequency of intake for 90 food items and 8 beverages. Using unconditional logistic regression, odds ratios, 95% confidence intervals, and p values for trend tests across quartiles of food consumption based on the frequency distribution of the control group were calculated. After controlling for age, race, body mass index, and total energy intake, we observed decreasing risk with increasing consumption of cooked tomatoes (p = 0.0011), summer squash (p = 0.0006), cauliflower (p = 0.0046), potato salad (p = 0.0086), tuna (p = 0.0053), and dark breads (p = 0.0599); while consumption of cantaloupe (p = 0.0109), fruit juice (p = 0.0044), milk on cereal (p = 0.0426), ice cream (p = 0.0350), hard candy (p = 0.0008), milk (not on cereal) (p = 0.0008), and cream/milk/creamer in tea/coffee (p = 0.0008) showed positive trends. Dietary factors have been examined in relation to myeloma in only handful of studies with some consistency suggesting decreased risk of MM associated with consumption of cruciferous and green vegetables, fish and whole grain foods, similar to the findings of our study.

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