172989 Cost-effectiveness of a WISEWOMAN behavioral weight loss intervention for low-income women: The Weight-Wise Program

Tuesday, October 28, 2008: 5:15 PM

Alison Gustafson, PhD, MPH, RD , Nutrition, University of Kentucky, Lexington, KY
Carmen D. Samuel-Hodge, PhD, MPH, RD , Center for Health Promotion and Disease Prevention and School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC
Olga Khavjou, MA , Research Triangle Institute, Research Triangle Park, NC
Beverly A. Garcia, MPH , Center for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, Chapel Hill, NC
Sara C. Lindsley, MS, BSN, RN , Center for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, Wilmington, NC
Kathryn P. Bramble, MA , Center for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, Wilmington, NC
Larry F. Johnston, MA , Center for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, Chapel Hill, NC
Thomas C. Keyserling, MD, MPH , Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC
Ziya Gizlice, PhD , Center for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, Chapel Hill, NC
Trisha E. Hardy, MPH, RD , University of North Carolina at Chapel Hill, McKing Consulting Corporation, Centers for Disease Control and Prevention, Atlanta, GA
Alice Ammerman, DrPH, RD , Nutrition, University of North Carolina, Chapel Hill, NC
To assess the cost-effectiveness of an evidence-based weight-loss intervention adapted for low-income midlife women participating in the Centers for Disease Control and Prevention (CDC) WISEWOMAN program. A randomized controlled trial testing a 16-week evidence-based intervention with women enrolled from one community health center.143 women (40 64 years old, mean BMI 35.1) randomized to one of two arms special intervention (n=72) and a wait-listed control group (n=71). Effectiveness measures included changes in weight, systolic and diastolic blood pressure, total cholesterol, and HDL cholesterol. Cost-effectiveness measures calculated Life Years Gained (LYG) from a reduction in coronary heart disease risk (CHD) based on a 10-year CHD risk algorithm. In addition, LYG were calculated from changes in weight, based on excess Years Life Lost (YLL) algorithm. The cost-effectiveness analysis assessed the incremental cost-effectiveness of providing the special intervention and was calculated as: [Cost of intervention] / [D in LYG from a reduction in CHD or Obesity Risk between intervention and control participants].Weight-Wise intervention participants had statistically significant decreases in weight (kg) [-4.4 95% CI (-5.6, - 3.2)] and in systolic blood pressure [-6.2 mm Hg, 95% CI (-10.6, -1.7)] compared to control participants. Total intervention cost of conducting Weight Wise was $13,699 and cost per participant in the intervention group, $190. The incremental cost per Life Year Gained (discounted) from a decrease in obesity was $1,462 and $4,750 from a decrease in CHD risk.

Our results suggest Weight-Wise intervention may be a cost-effective approach to improving the health of low-income women.

Learning Objectives:
Identify the relevance of cost-effectiveness in evaluating behavioral weight loss interventions Explain how to collect information to conduct a cost-effectiveness analysis for behavioral weight loss interventions Identify behavioral weight loss interventions that are cost-effective relative to other interventions

Keywords: Weight Management, Low-Income

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I have collected all data and have been author on development
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.