176028 Case-control study of Chronic Kidney Disease for Peripheral Vascular Disease and Coronary Artery Disease

Sunday, October 26, 2008

Shin Yi Jang , Samsung Medical Center & Cardiac and Vascular Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Shin Yi Jnag , School of Public Health, Seoul National University, Seoul, South Korea
Seung Wook Lee , Department of Public Health, Graduate School of Public Health, Seoul National University, Seoul, South Korea
Duk-Kyung Kim , Samsung Medical Center & Cardiac and Vascular Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Background: Previous studies have shown that peripheral vascular disease (PVD) is a coronary artery disease (CAD) risk equivalent. The objective of present study is to analyze and compare the chronic kidney disease (CKD) between PVD and CAD under hypothesis of existing CKD between PVD and CAD.

Methods: We included 412 patients with PVD, and 3,673 patients with CAD at the Cardiovascular Center and 3,835 persons with medical check up at the Health Promotion Center of Samsung Medical Center as a control group, Seoul, Korea, from Nov. 1994 through Nov. 2004. Subjects were classified into two groups based on their baseline Glomerular filtration rate: greater than or equal to 60 mL/min/1.73m2 (no CKD group), and less than 60 mL/min/1.73m2 (CKD group).

Results: Distribution of CKD for PVD, CHD, and Control group was 24.3%, 20.4%, and 10.2%, (p<0.001), respectively. Multiple logistic regression analysis, adjusted for age, gender, smoking, anemia, LDL cholesterol level, and modified metabolic syndrome using BMI instead of waist circumference, showed that there was significantly associated with CKD for PVD (OR 1.53, 95% CI 1.07-2.19, p<0.02) and CHD (OR 1.48, 95% CI 1.26-1.74, p<0.001). Conclusion: CKD is associated with both peripheral vascular disease and coronary artery disease in Korea.

Learning Objectives:
Chronic kidney disease is a major risk factor for end stage renal disease, cardiovascular disease and premature death. The aim of this study is to analyze and compare the chronic kidney disease (CKD) between PVD and CAD under hypothesis of equally existing CKD between PVD and CAD.

Keywords: Chronic (CVD), Epidemiology

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I'm a doctoral course student in school of public health, Seoul National University.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

See more of: Cardiovascular Disease Epidemiology Poster Session
See more of: Epidemiology