189220 Enhancing evidence-based capacity for evidence-based decision making with regard to introduction of new vaccines: Pan American Health Organization's ProVac initiative

Tuesday, October 28, 2008: 3:05 PM

Jon K. Andrus, MD , Fch-Im/paho, Pan American Health Organization, Washington, D.C., DC
Christiana Toscano, MD , Fch-Im/paho, Pan American Health Organization, Washington, D.C., DC
Lucia Helena De Oliveira, MPH , Fch-Im/paho, Pan American Health Organization, Washington, D.C., DC
Steve Landry, PhD , The Gates Foundation, Seattle, WA
Sue Goldie, MD, MPH , Harvard School of Public Health, Boston, MA
Orin Levine, PhD , Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Vance Dietz , Global Immunization Division, CDC, Atlanta, GA
The Pan American Health Organization (PAHO) estimates that 16,000 deaths occur annually in Latin America and the Caribbean (LAC) due to rotavirus diarrhea; each year, another 22,000 children die from invasive pneumococcal disease and 32,000 women die from cervical cancer caused by human papillomavirus. Vaccines against these priority diseases present opportunities for substantial gains in health, contributing to the achievement of the Millennium Development Goals. The relative value of these vaccines depends on disease burden, vaccine price, effective delivery strategies, and available resources for their introduction into National Immunization Programs. As these elements vary between countries, the decision to introduce new and more costly vaccines requires that policy decisions are grounded in high-quality evidence that reflects national conditions and programmatic capacity. This strategic approach departs from a history of policy driven by less formal regional and global mechanisms.

Since 2004, PAHO has spearheaded the ProVac Initiative, striving to enhance national evidenced-based capacity to make informed policy decisions on new vaccine introduction. The Bill and Melinda Gates Foundation, Centers for Disease Control and Prevention, World Health Organization, and the PneumoADIP and Rotavirus Vaccine Project of GAVI have been critical supporters. The work plan for 20082013 will continue to address the following objectives: strengthening policy infrastructure and process; developing and enhancing tools for economic analysis; collecting data and conducting analyses; making evidence-based decisions; effectively planning for vaccine introduction when appropriate; developing strategies to iteratively assess progress and periodically revisit key decisions; and promoting scientific, technical, and policy-relevant partnerships.

Learning Objectives:
1.List at least 5 criteria important for informed policy decisions in the introduction of new vaccines. 2. Describe examples for each of those criteria. 3. Cite three vaccines that appear to have the highest priority for vaccine introduction in the Americas. 4. Articulate how PAHO looks to provide future technical assistance to developing countries for accelerating control of cervical cancer.

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am the Lead Technical Advisor with the Immunization Unit at the Pan American Health Organization (PAHO).
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

See more of: Global Immunization
See more of: Epidemiology