225240 Using the Intervention Mapping Approach to Develop an Intervention to Increase Rural Minority Participation in Clinical Trials

Monday, November 8, 2010 : 2:30 PM - 2:50 PM

Bahby Banks, MPH , Cecil B. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC
Ebun Olubukonla Odeneye, MPH , Department of Health Behavior and Health Education, UNC Gillings School of Global Public Health, Chapel Hill, NC
Malika Roman Isler, PhD, MPH , NC TraCS Institute - Community Engagement Core, The University of North Carolina at Chapel Hill, Chapel Hill, NC
Margaret Miles, RN, PhD, FAAN , School of Nursing, UNC Chapel Hill, Chapel Hill, NC
Giselle Corbie-Smith, MD, MSc , TraCS Community Engagement Core, University of North Carolina-Chapel Hill, Chapel Hill, NC
Background: Minorities are disproportionately affected by HIV/AIDS in the rural Southeast, yet they are underrepresented in HIV clinical trials. Therefore, it is important that targeted culturally appropriate interventions support rural minorities' participation in HIV/AIDS research. Intervention mapping (IM) provides a structured, theory-based approach for developing such interventions. The following presentation highlights the development of a community-wide effort to increase rural minority participation in HIV clinical trials.

Methods: Qualitative data was collected from three data sources: people living with HIV/AIDS (n=35) community leaders (n= 40), and service providers (n= 36). This data informed the development matrices with: behavioral outcomes, environmental outcomes, and performance objectives. Each performance objective was mapped with changeable, theoretically-based determinants in a matrix. Methods and strategies were developed to reflect the influencing factors and desired outcomes in each matrix.

Results: The outcomes and objectives varied by target group to produce a total of five matrices (three behavioral and two environmental). The three behavioral outcomes included: 1) Eligible PLWHA will enroll in clinical trials, 2) Service providers will refer eligible PLWHA to clinical trials, and 3) Community leaders will support HIV/AIDS research. The environmental outcomes included: 1) Decreasing HIV stigma, and 2) Increasing HIV testing and care. Resultant methods and strategies used constructs from the Theory of Reasoned Action, Social Cognitive Theory, and Social Support Theory.

Conclusion: This intervention was developed using IM and resulted in a comprehensive community-based program. It is potentially replicable, and can assist rural service providers and PLWHA in making informed decisions regarding trial participation.

Learning Areas:
Implementation of health education strategies, interventions and programs
Planning of health education strategies, interventions, and programs
Public health or related education
Public health or related research
Social and behavioral sciences

Learning Objectives:
1. Describe a methodology used to develop an intervention to increase minority enrollment in clinical trials research 2. Discuss the advantages of using both theory and the Intervention Mapping approach to create the intervention

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I served as the research assistant on the study for two years and am currently authoring a manuscript on how the intervention mapping approach was used for the study.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

Back to: 3319.0: Increasing Minority Participation in HIV/AIDS Clinical Trials in Rural Southeastern Communities: A Public Health Imperative