Online Program

Oral health-related quality of life and total mortality: A prospective cohort study of Japanese dentists

Sunday, November 3, 2013

Mariko Naito, DDS, PhD, Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
Kenji Wakai, MD, PhD, Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
Toru Naito, DDS, PhD, Department of General Dentistry, Fukuoka Dental College, Fukuoka, Japan
Haruo Nakagaki, DDS, PhD, Aichi-Gakuin University, Nagoya, Japan
Nobuhiro Hanada, DDS, PhD, Department of Translational Research, Tsurumi University School of Dental Medicine, Yokohama, Japan
Takashi Kawamura, MD, PhD, Kyoto University Health Service, Kyoto, Japan
[Objectives] To date, few studies of oral health-related quality of life (OHQOL) and mortality have been conducted, while data in the literature suggest that health-related quality of life is a predictor of mortality. We investigated whether OHQOL is predictive of total mortality in males and females. [Methods] We analyzed data in the Longitudinal Evaluation of Multi-phasic, Odontological, and Nutritional Associations in Dentists (LEMONADE) cohort study. A total of 10,114 Japanese dentists (mean age ± standard deviation, 52.4 ± 12.1 years) were included in the analysis. From 2001 through 2006, they completed the baseline questionnaire on lifestyle and health factors, including the number of teeth lost and the General Oral Health Assessment Index (GOHAI), to measure OHQOL. GOHAI scores lower than the Japanese norm were classified as having a poor OHQOL. Using Cox proportional hazard models, hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated after adjusting for age and other potential confounding factors. [Results] The mean follow-up period was 7.7 years. Males with poor OHQOL at baseline showed an increased total mortality risk. The multivariable HRs for males and females with GOHAI scores lower than the Japanese norm were 1.43 (95% CI, 1.16-1.76) and 1.26 (95% CI, 0.56-2.84), respectively, for total mortality referring to the higher GOHAI scorers. The risk for total mortality in male was little changed even after further adjustment for the number of teeth lost (HR, 1.40; 95% CI, 1.13-1.73). [Conclusion] Our findings suggest that OHQOL is independently associated with total mortality in males.

Learning Areas:

Chronic disease management and prevention
Communication and informatics
Ethics, professional and legal requirements
Implementation of health education strategies, interventions and programs
Systems thinking models (conceptual and theoretical models), applications related to public health

Learning Objectives:
Demonstrate the association between oral health-related quality of life and total mortality in 10,114 dentists

Keyword(s): Epidemiology, Quality of Life

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am an epidemiologist and dentist. I have been the principal or co-principal of multiple Japanese government funded grants focusing on QOL/PRO (Patient reported outcomes) research. I have also involved in conducting a couple of large cohort study such as the LEMONADE study (more than 20,000 dentists enrolled) and the Japan Multi-Institutional Collaborative Cohort Study (90,000 people have enrolled). My scientific interests have been the impact of health-related QOL on mortality, morbidity and disability.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.