Adding to the HIV Prevention Toolkit: High Interest in a Long-Acting Injectable Formulation of Pre-Exposure Prophylaxis in a Cohort of Young Men who have Sex with Men in NYC
Methods: Between May-August 2013, a cross-sectional study was conducted with a racially/ethnically diverse cohort of YMSM in NYC. Three outcome measures were assessed: 1) willingness to use LAI-P; 2) preference for route of administration; and 3) major concerns with LAI-PrEP.
Results: Of 197 YMSM (74.1% of color), 80% responded that they would definitely/probably try LAI-P and 85.7% preferred injection every three months over daily oral administration. No difference in interest and preference was seen across groups by race/ethnicity, socioeconomic status, education, or risk behavior. Major concerns around LAI-P were side effects (87.8%,n=173), long-term health effects (85.8%,n=169) and uncertainty of drug’s effectiveness (83.3%,n=164). In addition, personal concerns such as risk disinhibition and stigma were noted: 47.2% stated they might be more likely to reduce their condom use if taking PrEP and 28.4% worried they would be mistaken as HIV-infected.
Conclusions: This study is the first to explore acceptability of LAI-P in the US. The significant preference for LAI-P over daily oral PrEP across all groups suggests that a LAI product would be a welcome addition to the prevention toolkit.
Learning Areas:Basic medical science applied in public health
Clinical medicine applied in public health
Implementation of health education strategies, interventions and programs
Public health or related education
Social and behavioral sciences
Compare the acceptability of long-acting injectable PrEP to daily oral PrEP in a racially and ethnically diverse cohort of young men who have sex with men.
Keyword(s): HIV/AIDS, Prevention
Qualified on the content I am responsible for because: I have participated in various quantitative clinical research projects addressing issues of HIV-1 pathogenesis and treatment. Recently, I have been co-investigator in a mixed methods research project investigating attitudes towards and behavioral correlates of interest in long-acting PrEP among MSM. In addition, I am a doctoral student at the CUNY graduate center.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.