142nd APHA Annual Meeting and Exposition

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302653
Improving Physical Activity After Cancer Treatment (IMPAACT): Effects of Aerobic and Resistance Training on Body Composition, Musculoskeletal Health, and Functional Capacity Among Cancer Survivors

142nd APHA Annual Meeting and Exposition (November 15 - November 19, 2014): http://www.apha.org/events-and-meetings/annual
Tuesday, November 18, 2014

Heather P. Tarleton, PhD, MS, MPAP , Department of Health and Human Sciences, Loyola Marymount University, Los Angeles, CA
Cancer survivors have a higher risk of developing osteoporosis and cardiovascular disease (CVD). The goal of the IMPAACT pilot study is to examine the effect of a combined program of aerobic and resistance training (CART) on reducing comorbidity and improving fitness among cancer survivors.  Participants were identified through convenience sampling in Los Angeles County. Eleven cancer survivors consented to 13-weeks of supervised CART (1 hour, 3 times/week).  The average age of participants was 57.8 years (SD 10.5) with 5 participants classified as overweight (BMI>25 kg/m2), 3 classified as obese (BMI>30 kg/m2), and 4 classified as osteopenic/osteoporotic.  At week 8, the average weight loss among participants was negligible (0.04 kg, SD 1.37). However, 4 of 9 participants experienced a >4 cm decrease in waist circumference with an average decrease in waist circumference of 2.74 cm (SD 2.19) for the cohort.  A 12.2% increase in isokinetic strength of the quadriceps (SD 8.0) at 60 deg/s suggests an increase in lean muscle mass.  Total bone density improved on average by 0.6% (SD 0.72) with T-scores maintained or improved at the hip.  Analysis of CRP, IL-6, IL-10, IGF-1, IGFBP-3, leptin, adiponectin, cortisol and bone formation and resorption markers will be presented. Analysis of heart rate variability and balance improvements will also be presented.  Preliminary findings suggest that cancer survivors can reduce their central adiposity and risk for CVD and also improve musculoskeletal health within a short period of time by engaging weekly in at least 180 minutes of CART.

Learning Areas:

Administer health education strategies, interventions and programs
Chronic disease management and prevention
Implementation of health education strategies, interventions and programs

Learning Objectives:
Discuss how a combined program of aerobic and resistance training can modify the effect of adiposity and biomarkers of inflammation and chronic stress on survival prognosis and risk for cancer recurrence. Assess whether physical activity interventions have short term or long term effects on biomarkers of bone formation and resorption and on musculoskeletal health (bone density, lean muscle mass). Compare observed improvements in functional capacity (muscle strength, balance, heart rate variability, cardiorespiratory fitness) among cancer survivors engaged in combined aerobic and resistance training with cancer survivors engaged in aerobic exercise only.

Keyword(s): Cancer and Women’s Health, Chronic Disease Management and Care

Presenting author's disclosure statement:

Qualified on the content I am responsible for because: I am a cancer and chronic disease epidemiologist and Principal Investigator of the IMPAACT Study at Loyola Marymount University. My research interests are in biological-environmental interactions and modifiable health behaviors. I am also interested in public health prevention through health education and interventions that are culturally and socioeconomically appropriate for diverse communities.
Any relevant financial relationships? No

I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.

Back to: 4080.0: Cancer Survivorship Research