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Pharmacological treatment for diabetes and cognitive impairment in older diabetic adults
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METHODS: This was a retrospective cross-sectional study using the nationally representative 2010 Health and Retirement Study. A weighted logistic regression was performed to obtain likelihood of having poor cognitive function while controlling for use of pharmacological treatment for diabetes, sex, race, education level, hypertension/ high blood pressure, smoking, and use of insulin.
Results: Of the weighted 440,572 eligible subjects with diabetes (unweighted N=96), 306,626 subjects (69.6%) took oral diabetes medications. Weighted logistic regression revealed that pharmacological treatment for diabetes was associated with a lower risk of cognitive impairment. Elderly with diabetes with medications were 1.37 times and 2.55 times more likely to have higher total word recall (OR=1.37, 95% CI=1.34-1.40) and mental score (OR=2.55, 95% CI=2.48-2.62) than those without medications, respectively. Similarly, those with medications were 2.16 times more likely to have higher total cognition score than those without medications (OR=2.16, 95% CI=2.11-2.22).
Conclusion: Pharmacological treatment for diabetes was associated with higher odds of better cognitive score. Therefore, further studies can explore the potential of the impact of pharmacological treatment on preventing cognitive impairment in the older diabetic adult population.
Learning Areas:
Public health or related researchLearning Objectives:
Identify the impacts of pharmacological treatment for diabetes on cognitive impairment in older adults with diabetes
Describe the potential of pharmacological treatment for diabetes to reduce risks of cognitive impairment in older adults with diabetes
Qualified on the content I am responsible for because: I am a doctoral student of Health Behavior at the Indiana University-Bloomington. My current research interests include the impacts of pharmacological treatment for diabetes in older adults population.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.