308080
Association of air pollution and cardiovascular mortality in Reykjavik, Iceland: A population based case-crossover study
Methods: Data on daily mortality were obtained from the National Cause-of-Death Registry, Statistics Iceland, during 2003 to 2009. One hour measures of NO2, O3, PM10, SO2, and H2S were obtained from the Environment Agency of Iceland for the same time period. A time-stratified case-crossover design was used to estimate the possible effect of short-term exposure of air pollution and cardiovascular mortality.
Results: The total number of deaths due to cardiovascular causes over the study period was 2,070 cases. The inter-quartile range (IQR) of the 24-hour concentration levels of NO2, O3, PM10, SO2, and H2S over the study period was 17 μg/m3, 20 μg/m3, 13 μg/m3, 2 μg/m3, 2 μg/m3, respectively. The association for IQR increases of the pollutants and cardiovascular mortality were not statistically significant at any time lag, with odds ratios near unity.
Conclusion: The pollution concentration levels in Reykjavík are generally low in an international perspective, but peaks of pollutants, such as PM10, may exceed peaks occurring in other European cities. Previous studies have implied that air pollution in Reykjavik could increase consumption of medicament against asthma and angina pectoris. However, there were no short-term associations between air pollution and cardiovascular mortality in the present study, contrary to what has been found elsewhere.
Learning Areas:
Environmental health sciencesEpidemiology
Public health or related research
Learning Objectives:
Explain the procedure of case-crossover studies
Discuss the use of mortality data from nation-wide registry
Discuss how to design and conduct an ecological study with adjustment for several risk factors
Keyword(s): Air Pollution & Respiratory Health, Mortality
Qualified on the content I am responsible for because: I am currently professor in Preventive Medicine at the University of Iceland, and my research and publications include assessment of environmental factors and the possible adverse effects to health.
Any relevant financial relationships? No
I agree to comply with the American Public Health Association Conflict of Interest and Commercial Support Guidelines, and to disclose to the participants any off-label or experimental uses of a commercial product or service discussed in my presentation.