Genetic testing for autism: Perceptions among Taiwanese parents of children with autism spectrum disorders

Autism Spectrum Disorders (ASD) is a major public health concern in Taiwan due to its high prevalence (12.3%). In fact, several genetic research projects focusing solely on ASD are trying to identity ASD-related genes for the Taiwanese population. Since, culture has a vast influence on the general perception of the public about genomic diseases and disabilities, it is critical to examine the attitude of the Taiwanese people towards ASD genetic testing before the provision of this test. The purpose of this first-of-its-kind qualitative study is to examine the attitude and opinion about ASD genetic testing among Taiwanese parents with ASD children.Semi-structured, in-depth interviews were conducted with a total of 39 parents who had at least one child diagnosed with ASD. The interviews were audio-taped and coded afterwards for content analysis using Nvivo8.Our preliminary data showed that majority of the parents (79.5%) indicated favorable attitudes towards ASD genetic testing. Parents discussed their opinion toward three specific types of ASD genetic testing –carrier testing, prenatal diagnosis, and newborn screening. The most preferred test was prenatal diagnosis (n=18, 46.2%). Parents believed this test could be used for early diagnosis and for timely preparation of the birth of affected children, termination of affected pregnancies, and for advancing research and benefiting the society.Most Taiwanese parents endorsed the idea of ASD genetic testing, especially prenatal diagnosis. This unique study provides critical information for the purposes of official guidelines, policies, and practice implications regarding ASD genetic testing before its comprehensive implementation in Taiwan.